One tip that I have been playing with to great effect has been this one:
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Hard Pan Out of Phase Electronic sounds can sound sterile and dry, so I look for ways to add color and dynamics. By dynamics, I mean soft, subtle changes. Tape simulators work well in that regard, as do plug-ins like the SansAmp.
One trick that I do with my Buchla Music Easel, which works with any synth, is to pan a sound hard left and right, but put the signal in each speaker out of phase from the other. The result is unique but doesn't clutter the mix. Then I might add spatial modulation to move the signal from side to side, often using randomly generated CVs to make it unpredictable.
--Joe Guido Welsh, writer/producer/multi instrumentalist (Thelonious Moog)
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http://www.emusician.com/eq-mag/0765/master-class-%E2%80%93-synth-secrets-of-the-pros/150346